Description
Recombinant Human ITGAIIb & ITGB3 Heterodimer Protein, His-tagged is expressed from human 293 cells (HEK293). It contains AA Leu 32 - Arg 993 (ITGAIIb) & Gly 27 - Asp 718 (ITGB3) (Accession # P08514-1 (R887L) (ITGAIIb) & P05106-1 (ITGB3)). Predicted N-terminus: Leu 32 (ITGAIIb) & Gly 27 (ITGB3). Human ITGAIIb & ITGB3 Heterodimer Protein, produced by co-expression of ITGAIIb and ITGB3, has a calculated MW of 111.4 kDa (ITGAIIb) & 81.8 kDa (ITGB3). Subunit ITGAIIb is fused with an acidic tail at the C-terminus and followed by a polyhistidine tag and subunit ITGB3 contains no tag but a basic tail at the C-terminus. The reducing (R) protein migrates as 125 kDa and 145 kDa (ITGAIIb) and 110-120 kDa (ITGB3) respectively due to glycosylation